Day -1 Monday, August 30,2010 |
7.30–8.30 AM |
Breakfast & Registration |
8.30–9.15 AM |
INAUGURAL CEREMONY |
Day 1 Session 1 |
9.15-09.35 AM |
The Indian and Global HIV Epidemic
- Recap early cases of HIV – Global/India
- Past and current trends in Indian and global epidemic
- HIV genetic diversity – subtypes
- Current approaches to prevent the sexual transmission of HIV infection
- Prevention approaches in trial
- Key findings in the prevention of MTCT
- Research priorities
|
09.35–09.55 AM |
Understanding HIV Pathogenesis and Recent Trends
- Mechanisms of HIV transmission through sexual route
- Immunopathogenesis and T-cell dynamics.
- Viral set-point and asymptomatic phase of HIV infection.
- Host and viral factors in disease progression.
- Exposed uninfected – Rapid Progressors - LTNP – Elite controllers
- Recent research updates
- Research priorities
|
09.55-10.15 AM |
Impact of Antiretroviral therapy on the Natural History of HIV disease
- Stages of HIV disease
- Disease progression and clinical manifestations
- Surrogate markers in HIV disease
- Spectrum of OIs among HIV patients in India – past and present trends
- Clinical management of HIV/AIDS and challenges in treatment
- NH of HIV differs from global scenario?
- Research priorities
|
Discussion (10.15 – 10.30 AM) |
Coffee Break (10.30 – 10.45 AM) |
Day 1 ; Session 2 |
10.45-11.00 AM |
HIV Testing : Pre and Post- Test Counseling
- Why counseling is important for HIV testing?
- Orientation to counseling and risk reduction counseling
- Pre and post test counseling –step wise approach with case discussions
- NACO/WHO policy guidelines
|
11.00-11.30 AM |
National/WHO Recommendations on HIV Testing and Blood Safety
- Updated HIV testing algorithms & strategies
- Issues associated with testing strategies using rapid tests
- Biological false positivity
- HIV testing in blood bank and national policy
- Review of diagnosing HIV infection in infants and young children
- Virologic and antibody tests & interpretation in infant diagnosis
- Use of Dried blood spots
- Research priorities
|
11.30- 11.50 AM |
HIV and Sexually Transmitted Diseases
- High-risk population and common STDs
- HIV transmission and influence of STDs
- Overview of clinical manifestations of STDs in HIV patients
- Limitations of lab diagnosis of STDs
- Syndromic management of STDs and its effectiveness in HIV prevention
- New, neglected, and uncommon STDs
- Recent research updates
- Research priorities
|
11.50-12.10 PM |
Co-infection: HIV and TB
- HIV and tuberculosis co-infections in India
- Impact of TB On HIV and HIV on TB – clinical manifestations
- Extra-pulmonary TB
- Role of BCG vaccination for HIV infected infants
- Recent research updates
- Research priorities
|
Discussion (12.10 - 12.25 PM) |
Day 1 Poster Session & Lunch Break (12.25-2.30 PM) |
Day 1 ; Session 3 |
2.30 – 2.50 PM |
Lessons to learn form HIV vaccine failure
- Recent research updates
- Research priorities
|
2.50 – 3.10 PM |
Challenges in HIV Preventive Vaccine Development
- Major challenges in HIV vaccine development
- Past experience and current approaches
- Recent research updates
- Research priorities
|
3.10 - 3.30 PM |
HIV Vaccine Trial : Current status and the Way Forward
- Gist of ongoing vaccine trials
- Outcome of recent vaccine clinical trials
- Ethical and regulatory issues and other challenges
|
3.30-3.50 PM |
Biomedical options for HIV prevention
- Different biomedical prevention options
- Risk versus success rate
- Recent research updates
|
Discussion ( 3.50 – 4.05 PM) |
Coffee Break ( 4.05 – 4.20 PM) |
Day 1 ; Session 4 |
4.20 – 4.40 PM |
Cellular immune defects in HIV infection: with special reference to NK cells and pDC
- Role of innate immunity in HIV infection.
- Recent research updates
- Research priorities
|
4.40 - 5.00 PM |
HIV-1 impairs in-vitro priming of naïve T cells and gives rise to contact-dependent suppressor T cells
- HIV pulsed DCs induce T cell impairment
- HIV primed T cells up-regulate certain negative stimulatory (suppressor T cells) molecules
- Suppressor T cells impair the function of other T cells in a contact-dependent manner
- Blockade of HIV induced suppressor molecules restores T cell function
- Research priorities
|
5.00 – 5.20 PM |
Biosignatures of negative T cell co-stimulation: Unveiling additional preprints of immune abrogation in HIV disease
- Mechanisms of T-cell dysfunction
- Negative co-stimulatory molecules and T cell regulation in HIV infection
- LAG-3, PD-1, CTLA-4, TRAIL etc. as negative factors of T cell impairment in HIV infection
- Association of Blimp-1 and Foxp3 as transcriptional regulators of T cell activation and proliferation
- Research priorities
|
Discussion (5.20 – 5.35 PM) |
Concluding Remarks & Closure of First Day Scientific Sessions |
Day 2 ; Session 1 ; Tuesday 31st August 2010 |
8.30-8.50 AM |
Opportunistic Infections in HIV - Mycotic
- Common mycotic OIs in HIV in India
- Overview of Indian literature
- Diagnostic methods for common mycotic OI & role of laboratory tests (sensitivity and specificity of common tests)
- Recent research updates
- Research priorities
|
8.50-9.10 AM |
Opportunistic/Co-infections in HIV - Parasitic
- Common parasitic OIs in HIV in India
- Overview of Indian literature
- Diagnostic methods for common parasitic OI & role of laboratory tests (sensitivity and specificity of common tests)
- Recent research updates
- Research priorities
|
9.10- 9.30 AM |
Co-infection: HIV and Filaria
- HIV and Filaria co-infections in India
- Interaction between HIV and Filaria
- Clinical manifestations in HIV patients
- Diagnostic issues
- Recent research updates
- Research priorities
|
9.30 – 9.50 AM |
Parasitic infections and HIV-associated immune reconstitution inflammatory syndrome (IRIS) in Indian scenario
- Immunological mechanisms of IRIS
- Diagnostic markers
- Recent research updates
- Research priorities
|
Discussion (9.50 – 10.05 AM) |
Coffee Break (10.05 – 10.20 AM) |
Day 2 ; Session 2 |
10.20 – 10.40 AM |
Immunogenetic Basis of HIV-1 Infection, Transmission and Disease Progression.
- AIDS restriction genes
- Role of host factors (mutations/polymorphisms in HIV co-receptors)
- Genetic basis of natural resistance to HIV.
- Genetic factors that modulate immune response and disease progression
- Recent research updates
- Research priorities
|
10.40 – 11.00 AM |
Drug Resistance in HIV and its current status among treated and untreated patients
- ART drug targets
- ART classes and their mode of action
- Evolution and mechanism of viral resistance
- Common mutations and its role drug resistance
- Polymorphisms and its role in drug resistance
- Resistance testing and its importance
- Recent research updates
- Research priorities
|
11.00 – 11.20 AM |
Newer Diagnostic Methodologies in HIV/AIDS
- Newer HIV diagnostic and monitoring methodologies
- Merits and demerits of each method
- Newer methodologies – OI diagnosis
- Recent research updates
- Research priorities
|
11.20-11.40 AM |
POC Testing for detection of fungal OIs in Resource-limited settings
- Impact of POC testing in resource-limited settings
- Performance characteristics of the tests
- Recent research updates
|
Discussion (11.40 – 11.55 AM) |
Day 2 Poster Session & Lunch Break (11.55 – 2.00 PM) |
Day 2 ; Session 3 |
2.00 – 2.20 PM |
HIV and Oral manifestations
- Oral manifestations in HIV disease
- Past and current trends
- Research priorities
|
2.20 – 2.40 PM |
Bio-safety in Healthcare Settings – National /WHO Guidelines
- Transmission of blood-borne pathogens in the health care setting
- Universal precautions and infection control methods
- Post-Exposure Prophylaxis and guidelines/national policy (NACO)
|
2.40 – 3.00 PM |
Post-exposure Prophylaxis
- Evaluation of risk
- Post-Exposure Prophylaxis (PEP) - guidelines/national policy (NACO)
- Do’s and don’ts after accidental exposures
- Common challenges faced in resource-limited settings
- How to overcome challenges
|
3.00 – 3.20 PM
|
Emerging Infectious Diseases and Future Research
- Combating emerging infectious diseases
- Research priorities for India
|
3.20 - 3.40 PM |
Bioethics in HIV/AIDS research
- Ethical issues in HIV/AIDS research
- National guidelines on bioethics
|
Discussion (3.40 – 3.55 PM) |
Distribution of Prize for Best Abstract/Posters, Closing Remarks & Vote of Thanks
by Prof. Suniti Solomon, MD, FAMS
|
COFFEE & CLOSURE |
